Targeting mitochondria for cardiovascular disorders: therapeutic potential and obstacles
نویسندگان
چکیده
منابع مشابه
Targeting Mitochondria as Therapeutic Strategy for Metabolic Disorders
Mitochondria are critical regulator of cell metabolism; thus, mitochondrial dysfunction is associated with many metabolic disorders. Defects in oxidative phosphorylation, ROS production, or mtDNA mutations are the main causes of mitochondrial dysfunction in many pathological conditions such as IR/diabetes, metabolic syndrome, cardiovascular diseases, and cancer. Thus, targeting mitochondria has...
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ژورنال
عنوان ژورنال: Nature Reviews Cardiology
سال: 2018
ISSN: 1759-5002,1759-5010
DOI: 10.1038/s41569-018-0074-0